Ovesse Estriol 1mg/g Vaginal Cream 15g Tube & Applicator

Ovesse Estriol 1 mg/g Vaginal Cream 15g is a prescription vaginal oestrogen treatment for women over 50+, applied with a reusable applicator. It addresses the underlying hormonal changes of genitourinary syndrome of menopause, helping ease symptoms linked to vaginal atrophy. The cream contains estriol, a form of female hormone that supplements the body’s reduced oestrogen after menopause and supports the restoration of healthy vaginal tissue.
Clinically proven to restore vaginal oestrogen to relieve:
• Dryness • Soreness • Burning • Itching • Painful intercourse

Directions for use:
How much to use: 1 applicator filled to the red line (0.5g of cream)
How often to use: Initial dose: 1 application daily for 2 weeks.
Maintenance dose: 1 application twice a week (leave 3 or 4 days between each dose).
Do not use more than the recommended dose.
Restarting treatment after a break: Read the package leaflet.

Warnings and cautions:
Certain conditions may be made worse during oestrogen treatment, see section 2 of the package leaflet for more information.

You may need to speak to your doctor before using Ovesse. Ask your pharmacist for advice if you: • Are receiving a type of HRT (including tablets or patches) that circulates in the blood • Have a history of endometriosis • Have a history of excessive thickening of the womb lining • Are switching from another vaginal oestrogen.

Stop using Ovesse and see a doctor immediately if you notice any of the following during treatment: • Any of the conditions mentioned in the 'DO NOT use Ovesse' section • Any new vaginal bleeding, spotting or itching • If you have endometriosis and your symptoms come back.
Seek prompt advice from your doctor if you: • Have yellowing of your skin or the whites of your eyes (jaundice) • Have a large rise in your blood pressure (symptoms may be headache, tiredness, dizziness) • Get migraine-like headaches which happen for the first time • Become pregnant.
You should inform your doctor at your next appointment that you are using Ovesse.

DO NOT use Ovesse if you:

• Are allergic to estriol or any of the other ingredients.
• Have or ever had womb or ovarian cancer.
• Have or recently had vaginal or genital bleeding, since you periods stopped due to the menopause.
• Have recent or suspected endometrial hyperplasia (or e.g. you have been referred for an ultrasound or your womb and are awaiting results).
• Have previously been treated with oestrogen only systemic HRT (without Progestogen) and you have not had your womb removed.
• Have any thickening, lump or scarring on your vulva.
• Have severe baginal itching, or itchy patches or rash on you vulva.
• Have a current vaginal infection prior to starting treatment.
• Have or ever had breast cancer, or have a lump / change in appearance in your breast, or nipple discharge.
• Have or ever had a blood clot in a vein.
• Have or ever had a heart attack, stroke or angina.
• Have a blood clotting disorder.
• Have liver disease and your liver function tests have not returned to normal.
• Have a rare condition called 'porphyria'.

Ingredients:
Estriol 1mg in 1g cream, other ingredients: Octyldodecanol, Cetyl Palmitate, Glycerin, Cety Alcohol*, Atearyl Alcohol*, Polysorbate 60, Sorbitan Stearate, Chlorhexidine Hydrochloride, Lactic Acid, Sodium Hydroxide to pH 4, Purified Water.
*can cause local reactions

Do not store above 25°C. Do not freeze. Keep out of the sight and reach of children.